In MB/U-MDT group, a decrease was observed only after completion of treatment, almost reaching baseline levels; the MB/R-MDT group remained high during all treatment. Table 3 Causes of MDT discontinuation. The main AE presented in this paper is part of the prospective Brazilian Clinical Trial for Uniform Multidrug Therapy of Leprosy (U-MDT/CT-BR). 17 17 Penna GO, Pontes MA, Cruz R, Gonçalves Hde S, Penna ML, Bührer-Sékula S. A clinical trial for uniform multidrug therapy for leprosy patients in Brazil: Rationale and design. Mem Inst Oswaldo Cruz. 2012;107:22-7. Red blood cells, hematocrit and hemoglobin levels analysis according to gender and groups of treatment, presented significant higher decrease on female patients.
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