folds to hero, Hero raises to $5, sb folds, Big Blind 3-bets to $18. A 12.37% 3-bet range from the big blind when facing a button open. It is uncommon for players at low stakes to flat 4-bets out of position (as facing challenging post-flop situations are often avoided by newcomers). Players at low stakes usually have a very low 5-bet frequency. Also, given our positional advantage, we will more easily be able to get to showdown on seemingly scary boards with middling hands (like 77 or 66). Suited connectors (and one-gappers) : Suited connectors like 76s, 87s, 98s and T9s do a fantastic job realizing their equity, as do suited one-gappers like J9s, T8s, etc. There are other hands that sorta fit into this category that make good calls as well, such as A5s, Q9s or K9s. Despite such combinations having a high amount of raw equity, the frequency at which they are dominated makes them very difficult to play.
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Also, females with severe form may die undiagnosed in a neonatal adrenal crisis more often than males [15]. Morning administration of 250 μg of synthetic ACTH followed by measurements of plasma Δ5-17-hydroxypregnenolone (5–17P), cortisol, Δ4-17-hydroxyprogesterone (17OHP), DHEA(S), and androstenedione can be used to improve the diagnostic process of 3βHSD2D [3, 13]. Hormonal criteria for the diagnosis of 3βHSD2D have been developed from a previous study [13], where hormonal profiles of patients with homozygous/compound heterogeneous HSD3B2 mutations and people with normal HSD3B2 genes were compared. ACTH stimulation test shows, apart from diminished cortisol, an exaggerated response and high level of Δ5-17-hydroxypregnenolone in patients with homozygous/compound heterozygous HSD3B2 mutations and varies according to patient age (Table 1) [13, 46].
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