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All these determinants make the comparison between studies cumbersome and should be taken into consideration while labelling a specimen as nondiagnostic and assessing the risk of malignancy [4]. Some of the studies stated that the operator experience and the number of passes made during FNA correlate with the nondiagnostic result [7, 8]. Mondal et al. and Nandedkar et al. found high incidence of category II lesions since the patients directly visit a tertiary care center for primary diagnosis without any referral which was also the case in our study [6, 9]. The implied risk of malignancy for category II is 0% to 3% with the recommended management being clinical follow-up of patients [2]. O que e taxa de registro consorcio volkswagen.Haja dinheiro para tanto giro! Portanto, não se esqueça de contabilizar a antebet nos seus cálculos de giros diários. Além disso, tenha paciência e privilegie os giros normais, que podem ser feitos até com alguns centavos.
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Our laboratory was following the ATA principles during the period of data collection for this study (2012–2017); therefore, among the malignant cases, three patients with WDT-UMP (11.1%) in Bethesda group III and one case (7.7%) in Bethesda group IV were considered at risk of malignancy [13, 14]. There were no cases of NIFTP among our thyroidectomy patients. The rates of malignancy for Bethesda III and IV nodules may vary among institutions, and they are likely to be higher in multicentre studies. In the literature, the malignancy rates for tumours in Bethesda categories are approximated as 10–30% for AUS/FLUS and 25–40% for FN/SFN (including NIFTP in malignant tumours) [4, 8]. In the present study, the malignancy rates for thyroid nodules diagnosed as Bethesda III and IV following resection (25 and 27.6%, respectively) are consistent with the literature. These rates may be considered to guide clinicians when deciding whether to perform a thyroidectomy, as well as to encourage pathologists to reconsider the current recommendations given by the Bethesda System for Reporting Thyroid Cytopathology. However, these results may not be generalisable to AUS/FLUS or FN/SFN cohorts, even though the rates are remarkedly similar to the rates observed in our study. In addition, other published cohorts with a smaller size have reported a malignancy risk for AUS/FLUS nodules as high as 46% [15, 17]. Differences in malignancy rates may be related to variability in randomisation, between institutions or in pathologic interpretation. Similar to our findings for Bethesda categories III and IV, Cavalheiro et al. also reported that PTC cases represented a majority of the malignant thyroid neoplasms [20]. In a cohort of 4827 cytological specimens, 806 cases were classified as AUS, among whom 255 patients underwent a thyroidectomy, with a malignancy rate of 39% [22].

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